Salicylic acid-13C6
Based on 1 Customer Validation
Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 1189678-81-6
- Formula: C13C6H6O3
- Molecular Weight:144.08
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1189678-81-6
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Unlabeled Cas 69-72-7
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Appearance Solid
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Molecular Weight 144.08
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Formula C13C6H6O3
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Color Off-white to light yellow
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SMILES
OC([13C]1=[13C]([13CH]=[13CH][13CH]=[13CH]1)O)=O
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Synonyms
2-Hydroxybenzoic acid-13C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 50 mg/mL (347.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 1 mg/mL (6.94 mM; Need ultrasonic)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (416 KB)
- English - EN (416 KB)
- Français - FR (416 KB)
- Deutsch - DE (416 KB)
- Norwegian - NO (416 KB)
- Español - ES (416 KB)
- Swedish - SV (416 KB)
- Italian - IT (416 KB)
- Korean - KR (416 KB)
- Portuguese - PT (416 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12.;Nixon M, et al. Salicylate downregulates 11 [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 6.9406 mL | 34.7029 mL | 69.4059 mL | 173.5147 mL |
| 5 mM | 1.3881 mL | 6.9406 mL | 13.8812 mL | 34.7029 mL | |
| DMSO | 10 mM | 0.6941 mL | 3.4703 mL | 6.9406 mL | 17.3515 mL |
| 15 mM | 0.4627 mL | 2.3135 mL | 4.6271 mL | 11.5676 mL | |
| 20 mM | 0.3470 mL | 1.7351 mL | 3.4703 mL | 8.6757 mL | |
| 25 mM | 0.2776 mL | 1.3881 mL | 2.7762 mL | 6.9406 mL | |
| 30 mM | 0.2314 mL | 1.1568 mL | 2.3135 mL | 5.7838 mL | |
| 40 mM | 0.1735 mL | 0.8676 mL | 1.7351 mL | 4.3379 mL | |
| 50 mM | 0.1388 mL | 0.6941 mL | 1.3881 mL | 3.4703 mL | |
| 60 mM | 0.1157 mL | 0.5784 mL | 1.1568 mL | 2.8919 mL | |
| 80 mM | 0.0868 mL | 0.4338 mL | 0.8676 mL | 2.1689 mL | |
| 100 mM | 0.0694 mL | 0.3470 mL | 0.6941 mL | 1.7351 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Salicylic acid-13C6 Related Classifications
HY-B0167S1 Related Classifications
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