69-72-7
69-72-7
Chemical Structure
Salicylic acid
Synonym(s): 2-Hydroxybenzoic acid
- CAS No.: 69-72-7
- Formula:C7H6O3
- Molecular Weight:138.12
IUPAC Name: 2-hydroxybenzoic acid
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC=C1O
Biological Activity: Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Salicylic acid has blood-brain barrier permeability[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Salicylic acid | 99.23% | Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Salicylic acid has blood-brain barrier permeability. | ||||||||||||||||||||
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Salicylic acid (Standard) | 98.00% | Salicylic acid (Standard) is the analytical standard of Salicylic acid. This product is intended for research and analytical applications. Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. | ||||||||||||||||||||
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2-Carboxyphenol-d4 | 99.83% | 2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens. | ||||||||||||||||||||
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Salicylic acid-13C6 | 95.47% | Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity. | ||||||||||||||||||||
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Salicylic acid-d6 | 99.82% | Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. | ||||||||||||||||||||
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References
- [1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12. [Content Brief]
- [2]. Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6. [Content Brief]
- [3]. Kang YS, et al. Acidic drug transport in vivo through the blood-brain barrier. A role of the transport carrier for monocarboxylic acids. J Pharmacobiodyn. 1990 Feb;13(2):158-63. [Content Brief]
