69-72-7
69-72-7
Chemical Structure
Salicylic acid
Synonym(s): 2-Hydroxybenzoic acid
- CAS No.: 69-72-7
- Formula:C7H6O3
- Molecular Weight:138.12
IUPAC Name: 2-hydroxybenzoic acid
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC=C1O
Biological Activity: Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Salicylic acid has blood-brain barrier permeability[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Salicylic acid | 99.23% | Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Salicylic acid has blood-brain barrier permeability. | ||||||||||||||||||||
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Salicylic acid (Standard) | 98.00% | Salicylic acid (Standard) is the analytical standard of Salicylic acid. This product is intended for research and analytical applications. Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. | ||||||||||||||||||||
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2-Carboxyphenol-d4 | 99.83% | 2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens. | ||||||||||||||||||||
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Salicylic acid-13C6 | 95.47% | Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity. | ||||||||||||||||||||
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Salicylic acid-d6 | 99.82% | Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. | ||||||||||||||||||||
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o-Toluic acid | 99.77% | O-toluic acid (2-Methylbenzoic acid) is an organic compound that is benzoic acid with a methyl group substituted at the 2-position. O-toluic acid can act as an exogenous metabolite and holds some chemical research value. | ||||||||||||||||||||
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o-Toluic acid-13C | 99% | o-Toluic acid-13C is the 13C labeled o-Toluic acid. o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite. | ||||||||||||||||||||
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p-Toluic acid-d4 | p-Toluic acid-d4 is the deuterium labeled p-Toluic acid. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc. | |||||||||||||||||||||
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Salicylamide | 99.72% | Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent. | ||||||||||||||||||||
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4-Aminobenzoic acid-d4 | 99.43% | 4-Aminobenzoic acid-d4 is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi. | ||||||||||||||||||||
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3-Aminobenzoic acid-d4 | 3-Aminobenzoic acid-d4 is the deuterium labeled 3-Aminobenzoic acid. | |||||||||||||||||||||
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Methyl paraben-d4 | 99.55% | Methyl paraben-d4 is the deuterium labeled Methyl Paraben. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity. | ||||||||||||||||||||
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Guaiacol-d4-1 | Guaiacol-d4-1 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity. | |||||||||||||||||||||
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p-Anisic acid-d4 | 99.9% | p-Anisic acid-d4 is the deuterium labeled p-Anisic acid. p-Anisic acid (4-Methoxybenzoic acid) is one of the isomers of anisic acid, with anti-bacterial and antiseptic properties. | ||||||||||||||||||||
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3-Hydroxyanthranilic acid | 99.79% | 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases. | ||||||||||||||||||||
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3-Hydroxybenzoic acid | 99.95% | 3-Hydroxybenzoic acid is an orally active endogenous metabolite. 3-Hydroxybenzoic acid is an agonist for GPR81 and GPR109A. 3-Hydroxybenzoic acid acts as stress response desensitizers. 3-Hydroxybenzoic acid can be used for anti-inflammatory and analgesic study. | ||||||||||||||||||||
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N-Methyliminodiacetic acid-d4 | 98.9% | 2,2'-(Methylazanediyl)diacetic acid-d4 is the deuterium labeled 2,2'-(Methylazanediyl)diacetic acid. | ||||||||||||||||||||
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4-Fluorobenzoic acid-13C,d4 | 4-Fluorobenzoic acid-13C,d4 is the 13C- and deuterium labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity. | |||||||||||||||||||||
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2-Hydroxymethyl benzoic acid | 97.30% | 2-Hydroxymethyl benzoic acid serves as an effective water substitute in the Passerini reaction. 2-Hydroxymethyl benzoic acid can be used for the synthesis of α-hydroxyamides, which are molecular building blocks for the synthesis of bioactive compounds. | ||||||||||||||||||||
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4-Bromobenzoic acid-d4 | 98.09% | 4-Bromobenzoic acid-d4 (Benzoic-2,3,5,6-d4 acid, 4-bromo- (9CI) is the d4-labeled 4-Bromobenzoic acid (HY-78700). 4-Bromobenzoic acid is a Dehalogenase substrate and intermediate. 4-Bromobenzoic acid undergoes hydrolytic dehalogenation catalyzed by the dehalogenase of Cupriavidus sp. strain SK-3 to produce 4-Hydroxybenzoic acid (HY-Y0264). 4-Bromobenzoic acid can be utilized as the sole carbon and energy source. 4-Bromobenzoic acid can be used for the synthesis of α-amylase inhibitors. | ||||||||||||||||||||
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4-Fluorobenzoic acid-d4 | 99.63% | 4-Fluorobenzoic acid-d4 is the deuterated-labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity. | ||||||||||||||||||||
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4-Chlorobenzoic acid-d4 | 4-Chlorobenzoic acid-d4 is the deuterium labeled 4-Chlorobenzoic acid-d4. | |||||||||||||||||||||
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3-Chlorobenzoic acid-d4 | 98.6% | 3-Chlorobenzoic acid-d4 is the deuterium labeled 3-Chlorobenzoic acid-d4. | ||||||||||||||||||||
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p-Anisic acid-d7 | p-Anisic acid-d7 (4-Methoxybenzoic acid-d7) is the deuterium labeled p-Anisic acid (HY-N1394). p-Anisic acid (4-Methoxybenzoic acid) is an orally available tyrosinase inhibitor that has antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, anti-diabetic, and preservative properties. p-Anisic acid can be used as a preservative in the cosmetics field. | |||||||||||||||||||||
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Methyl Salicylate-d4 | 99.8% | Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products. A systemic acquired resistance (SAR) signal in tobacco. A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor. | ||||||||||||||||||||
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Pyrocatechuic acid (Standard) | 99.62% | Pyrocatechuic acid (Standard) is the analytical standard of Pyrocatechuic acid. This product is intended for research and analytical applications. Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion. | ||||||||||||||||||||
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4-Hydroxybenzoic acid-d4 | 99.97% | 4-Hydroxybenzoic acid-d4 is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. | ||||||||||||||||||||
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2,6-Dihydroxybenzoic acid-d3 | 2,6-Dihydroxybenzoic acid-d3 is the deuterated-labeled 2,6-Dihydroxybenzoic acid (HY-Y0801). 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater. | |||||||||||||||||||||
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2-Fluorobenzoic acid | 99.64% | 2-Fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Benzoate-d5 sodium | 99.32% | Benzoate-d5 (sodium) is the deuterium labeled Sodium benzoate. | ||||||||||||||||||||
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2'-Hydroxyacetophenone (Standard) | ≥98% | 2'-Hydroxyacetophenone (Standard) is the analytical standard of 2'-Hydroxyacetophenone. This product is intended for research and analytical applications. 2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis. | ||||||||||||||||||||
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NSC 65593-d4 | 99.61% | NSC 65593-d4 is the deuterium labeled NSC 65593. | ||||||||||||||||||||
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References
- [1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12. [Content Brief]
- [2]. Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6. [Content Brief]
- [3]. Kang YS, et al. Acidic drug transport in vivo through the blood-brain barrier. A role of the transport carrier for monocarboxylic acids. J Pharmacobiodyn. 1990 Feb;13(2):158-63. [Content Brief]
