4-Fluorobenzoic acid-d₄

Name: 4-Fluorobenzoic acid-d 4
Brand: MedChemExpress
SKU: HY-W440239
Rating: 4.5 (1 reviews)

Cat. No.: HY-W440239: Data Sheet
SDS
Handling Instructions
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4-Fluorobenzoic-2,3,5,6-d₄ acid is the deuterium labeled 4-Fluorobenzoic-2,3,5,6 acid.

For research use only. We do not sell to patients.

4-Fluorobenzoic acid-d₄ Chemical Structure

CAS No. : 93111-25-2

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solid
1 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 4-Fluorobenzoic acid-d₄:

4-Fluorobenzoic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

4-Fluorobenzoic-2,3,5,6-d₄ acid is the deuterium labeled 4-Fluorobenzoic-2,3,5,6 acid^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

144.14

Formula

C₇HD₄FO₂

CAS No.

93111-25-2

Unlabeled CAS

456-22-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=C([2H])C([2H])=C(F)C([2H])=C1[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (693.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.9377 mL	34.6885 mL	69.3770 mL
5 mM	1.3875 mL	6.9377 mL	13.8754 mL
10 mM	0.6938 mL	3.4688 mL	6.9377 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Data Sheet (273 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.9377 mL	34.6885 mL	69.3770 mL	173.4425 mL
	5 mM	1.3875 mL	6.9377 mL	13.8754 mL	34.6885 mL
	10 mM	0.6938 mL	3.4688 mL	6.9377 mL	17.3442 mL
	15 mM	0.4625 mL	2.3126 mL	4.6251 mL	11.5628 mL
	20 mM	0.3469 mL	1.7344 mL	3.4688 mL	8.6721 mL
	25 mM	0.2775 mL	1.3875 mL	2.7751 mL	6.9377 mL
	30 mM	0.2313 mL	1.1563 mL	2.3126 mL	5.7814 mL
	40 mM	0.1734 mL	0.8672 mL	1.7344 mL	4.3361 mL
	50 mM	0.1388 mL	0.6938 mL	1.3875 mL	3.4688 mL
	60 mM	0.1156 mL	0.5781 mL	1.1563 mL	2.8907 mL
	80 mM	0.0867 mL	0.4336 mL	0.8672 mL	2.1680 mL
	100 mM	0.0694 mL	0.3469 mL	0.6938 mL	1.7344 mL