Succinic acid-d6
Based on 1 Customer Validation
Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 21668-90-6
- Formula: C4D6O4
- Molecular Weight:124.13
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 21668-90-6
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Unlabeled Cas 110-15-6
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Appearance Solid
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Molecular Weight 124.13
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Formula C4D6O4
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Color White to off-white
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SMILES
[2H]OC(C([2H])([2H])C([2H])([2H])C(O[2H])=O)=O
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Synonyms
Wormwood acid-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (805.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0561 mL | 40.2804 mL | 80.5607 mL | 201.4018 mL |
| 5 mM | 1.6112 mL | 8.0561 mL | 16.1121 mL | 40.2804 mL | |
| 10 mM | 0.8056 mL | 4.0280 mL | 8.0561 mL | 20.1402 mL | |
| 15 mM | 0.5371 mL | 2.6854 mL | 5.3707 mL | 13.4268 mL | |
| 20 mM | 0.4028 mL | 2.0140 mL | 4.0280 mL | 10.0701 mL | |
| 25 mM | 0.3222 mL | 1.6112 mL | 3.2224 mL | 8.0561 mL | |
| 30 mM | 0.2685 mL | 1.3427 mL | 2.6854 mL | 6.7134 mL | |
| 40 mM | 0.2014 mL | 1.0070 mL | 2.0140 mL | 5.0350 mL | |
| 50 mM | 0.1611 mL | 0.8056 mL | 1.6112 mL | 4.0280 mL | |
| 60 mM | 0.1343 mL | 0.6713 mL | 1.3427 mL | 3.3567 mL | |
| 80 mM | 0.1007 mL | 0.5035 mL | 1.0070 mL | 2.5175 mL | |
| 100 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0140 mL |
Succinic acid-d6 Related Classifications
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