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Cat. No.: HY-14605S

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Rasagiline-¹³C₃ mesylate

(Synonyms: (R)-AGN1135-13C3 mesylate; TVP1012-13C3 mesylate)

Rasagiline-¹³C₃ ((R)-AGN1135-¹³C₃; TVP1012-¹³C₃) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605). Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively.

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CAS No.: 1391052-18-8
Formule: C₁₀¹³C₃H₁₇NO₃S
Masse moléculaire:270.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Rasagiline-¹³C₃ mesylate Chemical Structure

CAS No.: 1391052-18-8

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Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
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Calculators
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Activité biologique

Description

Rasagiline-¹³C₃ ((R)-AGN1135-¹³C₃; TVP1012-¹³C₃) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605)^[1]. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively^[2].

Voir tous les produits spécifiques à Isoform Monoamine Oxidase :

MAO-A
MAO-B

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1391052-18-8
Unlabeled Cas 161735-79-1
Masse moléculaire 270.32
Formule C₁₀¹³C₃H₁₇NO₃S
SMILES

CS(=O)(O)=O.[13CH]#[13C][13CH2]N[C@H]1C2=CC=CC=C2CC1
Synonyms

(R)-AGN1135-13C3 mesylate; TVP1012-13C3 mesylate
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Rasagiline-¹³C₃ mesylate

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Rasagiline-13C3 mesylate

Voir tous les produits spécifiques à Isoform Monoamine Oxidase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Rasagiline-13C3 mesylate Related Classifications

HY-14605S Related Classifications

Rasagiline-¹³C₃ mesylate

Rasagiline-¹³C₃ mesylate Related Classifications