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Cat. No.: HY-14605S

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Rasagiline-¹³C₃ mesylate

(Synonyms: (R)-AGN1135-13C3 mesylate; TVP1012-13C3 mesylate)

Rasagiline-¹³C₃ ((R)-AGN1135-¹³C₃; TVP1012-¹³C₃) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605). Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively.

For research use only. We do not sell to patients.

CAS No.: 1391052-18-8
Formula: C₁₀¹³C₃H₁₇NO₃S
Molecular Weight:270.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Rasagiline-¹³C₃ mesylate Chemical Structure

CAS No.: 1391052-18-8

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Biological Activity

Description

Rasagiline-¹³C₃ ((R)-AGN1135-¹³C₃; TVP1012-¹³C₃) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605)^[1]. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively^[2].

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1391052-18-8
Unlabeled Cas 161735-79-1
Molecular Weight 270.32
Formula C₁₀¹³C₃H₁₇NO₃S
SMILES

CS(=O)(O)=O.[13CH]#[13C][13CH2]N[C@H]1C2=CC=CC=C2CC1
Synonyms

(R)-AGN1135-13C3 mesylate; TVP1012-13C3 mesylate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Rasagiline-13C3 mesylate

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Rasagiline-13C3 mesylate Related Classifications

HY-14605S Related Classifications

Rasagiline-¹³C₃ mesylate

Rasagiline-¹³C₃ mesylate Related Classifications