Hordenine-d6
Based on 1 Customer Validation
Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 1346598-66-0
- Formula: C10H9D6NO
- Molecular Weight:171.27
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1346598-66-0
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Unlabeled Cas 539-15-1
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Appearance Solid
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Molecular Weight 171.27
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Formula C10H9D6NO
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Color White to off-white
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SMILES
[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCC1=CC=C(C=C1)O
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Synonyms
Ordenina-d6; Peyocactine-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMF : ≥ 25 mg/mL (145.97 mM)
DMSO : ≥ 20 mg/mL (116.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 5 mg/mL (29.19 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kim SC, et al. Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes. Food Chem. 2013 Nov 1;141(1):174-81. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO / DMF | 1 mM | 5.8387 mL | 29.1937 mL | 58.3873 mL | 145.9684 mL |
| 5 mM | 1.1677 mL | 5.8387 mL | 11.6775 mL | 29.1937 mL | |
| 10 mM | 0.5839 mL | 2.9194 mL | 5.8387 mL | 14.5968 mL | |
| 15 mM | 0.3892 mL | 1.9462 mL | 3.8925 mL | 9.7312 mL | |
| 20 mM | 0.2919 mL | 1.4597 mL | 2.9194 mL | 7.2984 mL | |
| 25 mM | 0.2335 mL | 1.1677 mL | 2.3355 mL | 5.8387 mL | |
| DMSO / DMF | 30 mM | 0.1946 mL | 0.9731 mL | 1.9462 mL | 4.8656 mL |
| 40 mM | 0.1460 mL | 0.7298 mL | 1.4597 mL | 3.6492 mL | |
| 50 mM | 0.1168 mL | 0.5839 mL | 1.1677 mL | 2.9194 mL | |
| 60 mM | 0.0973 mL | 0.4866 mL | 0.9731 mL | 2.4328 mL | |
| 80 mM | 0.0730 mL | 0.3649 mL | 0.7298 mL | 1.8246 mL | |
| 100 mM | 0.0584 mL | 0.2919 mL | 0.5839 mL | 1.4597 mL |
Hordenine-d6 Related Classifications
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