DL-Aspartic acid-d3
Based on 1 Customer Validation
DL-Aspartic acid-d3 is the deuterium labeled L-Aspartic acid. L-Aspartic aicd is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions.
For research use only. We do not sell to patients.
- Purity: 99.56%
- CAS No.: 14341-75-4
- Formula: C4H4D3NO4
- Molecular Weight:136.12
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All Endogenous Metabolite Isoforms
More
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 14341-75-4
-
Unlabeled Cas 617-45-8
-
Appearance Solid
-
Molecular Weight 136.12
-
Formula C4H4D3NO4
-
Color White to off-white
-
SMILES
NC(C([2H])([2H])C(O)=O)([2H])C(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M NaOH : 100 mg/mL (734.65 mM; ultrasonic and adjust pH to 11 with 1 M NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. [Content Brief]
[2]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406. [Content Brief]
[3]. Su G, et al. Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. Redox Biol. 2024 May;71:103112. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M NaOH | 1 mM | 7.3465 mL | 36.7323 mL | 73.4646 mL | 183.6615 mL |
| 5 mM | 1.4693 mL | 7.3465 mL | 14.6929 mL | 36.7323 mL | |
| 10 mM | 0.7346 mL | 3.6732 mL | 7.3465 mL | 18.3661 mL | |
| 15 mM | 0.4898 mL | 2.4488 mL | 4.8976 mL | 12.2441 mL | |
| 20 mM | 0.3673 mL | 1.8366 mL | 3.6732 mL | 9.1831 mL | |
| 25 mM | 0.2939 mL | 1.4693 mL | 2.9386 mL | 7.3465 mL | |
| 30 mM | 0.2449 mL | 1.2244 mL | 2.4488 mL | 6.1220 mL | |
| 40 mM | 0.1837 mL | 0.9183 mL | 1.8366 mL | 4.5915 mL | |
| 50 mM | 0.1469 mL | 0.7346 mL | 1.4693 mL | 3.6732 mL | |
| 60 mM | 0.1224 mL | 0.6122 mL | 1.2244 mL | 3.0610 mL | |
| 80 mM | 0.0918 mL | 0.4592 mL | 0.9183 mL | 2.2958 mL | |
| 100 mM | 0.0735 mL | 0.3673 mL | 0.7346 mL | 1.8366 mL |
DL-Aspartic acid-d3 Related Classifications
HY-N0666S2 Related Classifications
Powered by Bioz