1. Protein Tyrosine Kinase/RTK
    Autophagy
  2. Bcr-Abl
    PDGFR
    c-Kit
    Autophagy
  3. Imatinib D8

Imatinib D8 (Synonyms: STI571 D8; CGP-57148B D8)

Cat. No.: HY-15463S
Handling Instructions

Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity.

For research use only. We do not sell to patients.

Imatinib D8 Chemical Structure

Imatinib D8 Chemical Structure

CAS No. : 1092942-82-9

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Description

Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].

Molecular Weight

501.65

Formula

C₂₉H₂₃D₈N₇O

CAS No.

1092942-82-9

SMILES

O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5C([2H])([2H])C([2H])([2H])N(C)C([2H])([2H])C5([2H])[2H])C=C4

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Imatinib D8STI571 D8CGP-57148B D8Imatinib D 8Imatinib D-8Bcr-AblPDGFRc-KitAutophagyPlatelet-derived growth factor receptorSCFRCD117deuteriumImatinibtyrosinekinasesautophosphorylationInhibitorinhibitorinhibit

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