Colfosceril miristate-d9
Based on 1 Customer Validation
Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 71479-88-4
- Formula: C36H63D9NO8P
- Molecular Weight:686.99
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 71479-88-4
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Unlabeled CAS 18194-24-6
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Appearance Solid
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Molecular Weight 686.99
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Formula C36H63D9NO8P
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Color White to off-white
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SMILES
CCCCCCCCCCCCCC(O[C@H](COC(CCCCCCCCCCCCC)=O)COP(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([O-])=O)=O
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Synonyms
DMPC-d9; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
Ethanol : 50 mg/mL (72.78 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2166-2174. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.4556 mL | 7.2781 mL | 14.5563 mL | 36.3906 mL |
| 5 mM | 0.2911 mL | 1.4556 mL | 2.9113 mL | 7.2781 mL | |
| 10 mM | 0.1456 mL | 0.7278 mL | 1.4556 mL | 3.6391 mL | |
| 15 mM | 0.0970 mL | 0.4852 mL | 0.9704 mL | 2.4260 mL | |
| 20 mM | 0.0728 mL | 0.3639 mL | 0.7278 mL | 1.8195 mL | |
| 25 mM | 0.0582 mL | 0.2911 mL | 0.5823 mL | 1.4556 mL | |
| 30 mM | 0.0485 mL | 0.2426 mL | 0.4852 mL | 1.2130 mL | |
| 40 mM | 0.0364 mL | 0.1820 mL | 0.3639 mL | 0.9098 mL | |
| 50 mM | 0.0291 mL | 0.1456 mL | 0.2911 mL | 0.7278 mL | |
| 60 mM | 0.0243 mL | 0.1213 mL | 0.2426 mL | 0.6065 mL |
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