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  3. L-Arginine-15N4 hydrochloride

L-Arginine-15N4 hydrochloride  (Synonyms: (S)-(+)-Arginine-15N4 hydrochloride)

Cat. No.: HY-N0455AS1 Purity: ≥98.0%
COA Handling Instructions

L-Arginine-15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].

For research use only. We do not sell to patients.

L-Arginine-<sup>15</sup>N<sub>4</sub> hydrochloride Chemical Structure

L-Arginine-15N4 hydrochloride Chemical Structure

CAS No. : 204633-95-4

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1 mg USD 50 In-stock
5 mg USD 150 In-stock
10 mg USD 270 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Arginine-15N4 hydrochloride:

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Description

L-Arginine-15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

214.64

Formula

C6H15Cl15N4O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[15NH]=C([15NH2])[15NH]CCC[C@H]([15NH2])C(O)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1164.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6590 mL 23.2948 mL 46.5896 mL
5 mM 0.9318 mL 4.6590 mL 9.3179 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6590 mL 23.2948 mL 46.5896 mL 116.4741 mL
5 mM 0.9318 mL 4.6590 mL 9.3179 mL 23.2948 mL
10 mM 0.4659 mL 2.3295 mL 4.6590 mL 11.6474 mL
15 mM 0.3106 mL 1.5530 mL 3.1060 mL 7.7649 mL
20 mM 0.2329 mL 1.1647 mL 2.3295 mL 5.8237 mL
25 mM 0.1864 mL 0.9318 mL 1.8636 mL 4.6590 mL
30 mM 0.1553 mL 0.7765 mL 1.5530 mL 3.8825 mL
40 mM 0.1165 mL 0.5824 mL 1.1647 mL 2.9119 mL
50 mM 0.0932 mL 0.4659 mL 0.9318 mL 2.3295 mL
60 mM 0.0776 mL 0.3882 mL 0.7765 mL 1.9412 mL
80 mM 0.0582 mL 0.2912 mL 0.5824 mL 1.4559 mL
100 mM 0.0466 mL 0.2329 mL 0.4659 mL 1.1647 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Product Name:
L-Arginine-15N4 hydrochloride
Cat. No.:
HY-N0455AS1
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