L-Arginine-¹⁵N₂ hydrochloride (Synonyms: (S)-(+)-Arginine-¹⁵N₂ hydrochloride)

Name: L-Arginine- 15 N 2 hydrochloride
Brand: MedChemExpress
SKU: HY-N0455AS
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0455AS Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Arginine-¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

For research use only. We do not sell to patients.

L-Arginine-<sup>15</sup>N<sub>2</sub> hydrochloride Chemical Structure

L-Arginine-¹⁵N₂ hydrochloride Chemical Structure

CAS No. : 204633-92-1

Size	Price	Stock	Quantity
5 mg	USD 193	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 600	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 960	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Arginine-¹⁵N₂ hydrochloride:

L-Arginine hydrochloride In-stock
L-Arginine-¹³C₆,d₁₄ hydrochloride Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

212.65

Formula

C₆H₁₅ClN₂¹⁵N₂O₂

CAS No.

204633-92-1

Appearance

Solid

Color

White to off-white

SMILES

N[C@H](C(O)=O)CCCNC([15NH2])=[15NH].Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : ≥ 25 mg/mL (117.56 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7026 mL	23.5128 mL	47.0256 mL
5 mM	0.9405 mL	4.7026 mL	9.4051 mL
10 mM	0.4703 mL	2.3513 mL	4.7026 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (394 KB)

COA (245 KB) HNMR (277 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [Content Brief]

[3]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [Content Brief]

[4]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.7026 mL	23.5128 mL	47.0256 mL	117.5641 mL
	5 mM	0.9405 mL	4.7026 mL	9.4051 mL	23.5128 mL
	10 mM	0.4703 mL	2.3513 mL	4.7026 mL	11.7564 mL
	15 mM	0.3135 mL	1.5675 mL	3.1350 mL	7.8376 mL
	20 mM	0.2351 mL	1.1756 mL	2.3513 mL	5.8782 mL
	25 mM	0.1881 mL	0.9405 mL	1.8810 mL	4.7026 mL
	30 mM	0.1568 mL	0.7838 mL	1.5675 mL	3.9188 mL
	40 mM	0.1176 mL	0.5878 mL	1.1756 mL	2.9391 mL
	50 mM	0.0941 mL	0.4703 mL	0.9405 mL	2.3513 mL
	60 mM	0.0784 mL	0.3919 mL	0.7838 mL	1.9594 mL
	80 mM	0.0588 mL	0.2939 mL	0.5878 mL	1.4696 mL
	100 mM	0.0470 mL	0.2351 mL	0.4703 mL	1.1756 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

L-Arginine-¹⁵N₂ hydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Arginine-¹⁵N₂204633-92-1(S)-(+)-Arginine-¹⁵N₂NO SynthaseEndogenous MetaboliteNitric oxide synthasesNOSInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name			Lot #
Applicant Name *			Email Address *
Phone Number			Department *
Organization Name *			Country or Region *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

L-Arginine-15N2 hydrochloride (Synonyms: (S)-(+)-Arginine-15N2 hydrochloride)

Customer Review

Other Forms of L-Arginine-15N2 hydrochloride:

L-Arginine-15N2 hydrochloride Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

L-Arginine-15N2 hydrochloride Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

L-Arginine-15N2 hydrochloride Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

Request for HNMR Report

L-Arginine-¹⁵N₂ hydrochloride (Synonyms: (S)-(+)-Arginine-¹⁵N₂ hydrochloride)

Other Forms of L-Arginine-¹⁵N₂ hydrochloride:

L-Arginine-¹⁵N₂ hydrochloride Related Antibodies

L-Arginine-¹⁵N₂ hydrochloride Related Antibodies

L-Arginine-¹⁵N₂ hydrochloride Related Classifications