L-Arginine-13C6,15N4 hydrochloride
Based on 1 Customer Validation
L-Arginine-13C6,15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 202468-25-5
- Formula: 13C6H15Cl15N4O2
- Molecular Weight:220.59
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 202468-25-5
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Unlabeled CAS 1119-34-2
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Appearance Solid
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Molecular Weight 220.59
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Formula 13C6H15Cl15N4O2
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Color White to off-white
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SMILES
[15NH]=[13C]([15NH2])[15NH][13CH2][13CH2][13CH2][13C@H]([15NH2])[13C](O)=O.Cl
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Synonyms
(S)-(+)-Arginine-13C6,15N4 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (453.33 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.5333 mL | 22.6665 mL | 45.3330 mL | 113.3324 mL |
| 5 mM | 0.9067 mL | 4.5333 mL | 9.0666 mL | 22.6665 mL | |
| 10 mM | 0.4533 mL | 2.2666 mL | 4.5333 mL | 11.3332 mL | |
| 15 mM | 0.3022 mL | 1.5111 mL | 3.0222 mL | 7.5555 mL | |
| 20 mM | 0.2267 mL | 1.1333 mL | 2.2666 mL | 5.6666 mL | |
| 25 mM | 0.1813 mL | 0.9067 mL | 1.8133 mL | 4.5333 mL | |
| 30 mM | 0.1511 mL | 0.7555 mL | 1.5111 mL | 3.7777 mL | |
| 40 mM | 0.1133 mL | 0.5667 mL | 1.1333 mL | 2.8333 mL | |
| 50 mM | 0.0907 mL | 0.4533 mL | 0.9067 mL | 2.2666 mL | |
| 60 mM | 0.0756 mL | 0.3778 mL | 0.7555 mL | 1.8889 mL | |
| 80 mM | 0.0567 mL | 0.2833 mL | 0.5667 mL | 1.4167 mL | |
| 100 mM | 0.0453 mL | 0.2267 mL | 0.4533 mL | 1.1333 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.