MtTMPK-IN-7
MtTMPK-IN-7 (compound 26) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 47 μM. MtTMPK-IN-7 has sub-micromolar activity against mycobacteria (MICs = 2.3~4.7 μM) without significant cytotoxicity. MtTMPK-IN-7 can be used for researching tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 2987482-25-5
- Formula: C27H29ClN6O3
- Molecular Weight:521.01
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
IC50: 47 μM (MtbTMPK)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | CC50 |
>64 μM
Compound: 26
|
Cytotoxicity against human MRC5 cells measured after 24 hrs by neutral red uptake assay
Cytotoxicity against human MRC5 cells measured after 24 hrs by neutral red uptake assay
|
[PMID: 32823003] |
Chemical Information
-
CAS No. 2987482-25-5
-
Molecular Weight 521.01
-
Formula C27H29ClN6O3
-
SMILES
CCC1=C(N2C=C(C=CC2=N1)Cl)C(NCC3=CC=C(C=C3)N4CCC(CC4)N5C=C(C(NC5=O)=O)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz