2987482-25-5
Chemical Structure
MtTMPK-IN-7
- CAS No.: 2987482-25-5
- Formula:C27H29ClN6O3
- Molecular Weight:521.01
IUPAC Name: 6-chloro-2-ethyl-N-(4-(4-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide
InChIKey: FXBYHKZKOADXDT-UHFFFAOYSA-N
SMILES: CCC1=C(N2C=C(C=CC2=N1)Cl)C(NCC3=CC=C(C=C3)N4CCC(CC4)N5C=C(C(NC5=O)=O)C)=O
Biological Activity: MtTMPK-IN-7 (compound 26) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 47 μM. MtTMPK-IN-7 has sub-micromolar activity against mycobacteria (MICs = 2.3~4.7 μM) without significant cytotoxicity. MtTMPK-IN-7 can be used for researching tuberculosis[1].
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MtTMPK-IN-7 | MtTMPK-IN-7 (compound 26) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 47 μM. MtTMPK-IN-7 has sub-micromolar activity against mycobacteria (MICs = 2.3~4.7 μM) without significant cytotoxicity. MtTMPK-IN-7 can be used for researching tuberculosis. | |||||||||||||||||||||
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Keywords
