2-Deoxy-D-glucose-d
Based on 1 publication(s) in Google Scholar
2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 188004-07-1
- Formula: C6H11DO5
- Molecular Weight:165.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 2-Deoxy-D-glucose-d
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 188004-07-1
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Unlabeled Cas 154-17-6
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Appearance Solid
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Molecular Weight 165.16
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Formula C6H11DO5
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Color White to off-white
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SMILES
O=C([2H])C[C@@H](O)[C@H](O)[C@H](O)CO
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Synonyms
2-DG-d1; 2-Deoxy-D-arabino-hexose-d1; D-Arabino-2-deoxyhexose-d1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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BMC Biotechnol
A TXNIP-driven bioluminescent reporter for high-throughput discovery of glycolytic inhibitors against renal cell carcinoma. [Abstract]2026 Feb 14;26(1):31. PMID: 41688960
Solvent & Solubility
H2O : 250 mg/mL (1513.68 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.0547 mL | 30.2737 mL | 60.5473 mL | 151.3684 mL |
| 5 mM | 1.2109 mL | 6.0547 mL | 12.1095 mL | 30.2737 mL | |
| 10 mM | 0.6055 mL | 3.0274 mL | 6.0547 mL | 15.1368 mL | |
| 15 mM | 0.4036 mL | 2.0182 mL | 4.0365 mL | 10.0912 mL | |
| 20 mM | 0.3027 mL | 1.5137 mL | 3.0274 mL | 7.5684 mL | |
| 25 mM | 0.2422 mL | 1.2109 mL | 2.4219 mL | 6.0547 mL | |
| 30 mM | 0.2018 mL | 1.0091 mL | 2.0182 mL | 5.0456 mL | |
| 40 mM | 0.1514 mL | 0.7568 mL | 1.5137 mL | 3.7842 mL | |
| 50 mM | 0.1211 mL | 0.6055 mL | 1.2109 mL | 3.0274 mL | |
| 60 mM | 0.1009 mL | 0.5046 mL | 1.0091 mL | 2.5228 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7568 mL | 1.8921 mL | |
| 100 mM | 0.0605 mL | 0.3027 mL | 0.6055 mL | 1.5137 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
2-Deoxy-D-glucose-d Related Classifications
HY-13966S Related Classifications
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