2-Phenylethanol-¹³C₂  (Synonyms: Phenylethyl alcohol-¹³C₂; Phenethyl alcohol-¹³C₂; Benzyl carbinol-¹³C₂)

2-Phenylethanol-¹³C₂ is ¹³C labeled β-Caryophyllene (HY-B1290). β-Caryophyllene is a CB2 receptor agonist.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
2-Phenylethanol is used as an additive in cigarettes and a preservative in soaps^[2].
2-Phenylethanol exerts an inhibitory effect on the growth of Gram-negative microorganisms^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Phenylethanol (5%; inhalation) increases anxiety-like behavior and decreases depression-like behavior in mice^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

124.15

C₆¹³C₂H₁₀O

68661-17-6

O[13CH2][13CH2]C1=CC=CC=C1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. M M W Etschmann, et al. Biotechnological production of 2-phenylethanol. Appl Microbiol Biotechnol. 2002 Jun;59(1):1-8.  [Content Brief]

  [3]. Y.-J. Zhu et al. Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid. Food Chemistry 124 (2011) 298-302.

  [4]. Hiroshi Ueno, et al. Anti-depressive-like effect of 2-phenylethanol inhalation in mice. Biomed Pharmacother. 2019 Mar:111:1499-1506.  [Content Brief]