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  2. Isotope-Labeled Compounds Adrenergic Receptor
  3. (S)-Timolol-d9 maleate

(S)-Timolol-d9 maleate  (Synonyms: (S)-L-714,465-d9 maleate; MK 950-d9)

Cat. No.: HY-17380S
Handling Instructions

(S)-Timolol-d9 (maleate) is deuterium labeled (S)-Timolol (Maleate). (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction[1][2][3].

For research use only. We do not sell to patients.

(S)-Timolol-d<sub>9</sub> maleate Chemical Structure

(S)-Timolol-d9 maleate Chemical Structure

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Description

(S)-Timolol-d9 (maleate) is deuterium labeled (S)-Timolol (Maleate). (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

441.55

Formula

C17H19D9N4O7S

SMILES

O[C@H](COC1=NSN=C1N2CCOCC2)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H].O=C(O)/C=C\C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(S)-Timolol-d9 maleate
Cat. No.:
HY-17380S
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