Semicarbazide-13C,15N2 hydrochloride
Based on 1 Customer Validation
Semicarbazide-13C,15N2 (Aminourea-13C,15N2) hydrochloride is the 13C- and 15N-labeled Semicarbazide hydrochloride (HY-Y0470). Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 1173020-16-0
- Formula: 13CH6ClN15N2O
- Molecular Weight:114.51
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1173020-16-0
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Unlabeled Cas 563-41-7
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Appearance Solid
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Molecular Weight 114.51
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Formula 13CH6ClN15N2O
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Color White to off-white
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SMILES
N[13C]([15NH][15NH2])=O.Cl
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Synonyms
Aminourea-13C,15N2 hydrochloride; Hydrazinecarboxamide-13C,15N2 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (806 KB)
- English - EN (806 KB)
- Français - FR (806 KB)
- Deutsch - DE (806 KB)
- Norwegian - NO (806 KB)
- Español - ES (806 KB)
- Swedish - SV (806 KB)
- Italian - IT (806 KB)
- Korean - KR (806 KB)
- Portuguese - PT (806 KB)
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Handling Instructions (2659 KB)
References
[1]. Adam Becalski, et al. Semicarbazide Formation in Azodicarbonamide-Treated Flour: A Model Study. J Agric Food Chem. 2004 Sep 8;52(18):5730-4. [Content Brief]
[2]. Hernandez M, et al. Soluble semicarbazide sensitive amine oxidase (SSAO) catalysis induces apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 2006 Feb;1763(2):164-73. [Content Brief]
[3]. Takahashi M, et al. Chronic toxicity and carcinogenicity of semicarbazide hydrochloride in Wistar Hannover GALAS rats. Food Chem Toxicol. 2014 Nov;73:84-94. [Content Brief]
[4]. Takahashi M, et al. Age-related susceptibility to induction of osteochondral and vascular lesions by semicarbazide hydrochloride in rats. Toxicol Pathol. 2010 Jun;38(4):598-605. [Content Brief]
[8]. Maranghi F, et al. Effects of the food contaminant semicarbazide following oral administration in juvenile Sprague-Dawley rats. Food Chem Toxicol. 2009 Feb;47(2):472-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Semicarbazide-13C,15N2 hydrochloride Related Classifications
HY-W067028S Related Classifications
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