563-41-7
563-41-7
Chemical Structure
Semicarbazide hydrochloride
Synonym(s): Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride
- CAS No.: 563-41-7
- Formula:CH6ClN3O
- Molecular Weight:111.53
IUPAC Name: hydrazinecarboxamide hydrochloride
InChIKey: XHQYBDSXTDXSHY-UHFFFAOYSA-N
SMILES: NNC(N)=O.[H]Cl
Biological Activity: Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles[1][2][3][4][5][6][7][8][9].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Semicarbazide hydrochloride | 98.0% | Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles. | ||||||||||||||||||||
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Semicarbazide hydrochloride (Standard) | 98.7% | Semicarbazide(hydrochloride (Standard) (Aminourea hydrochloride (Standard)) is the analytical standard of Semicarbazide hydrochloride (HY-Y0470). This product is intended for research and analytical applications. Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles. | ||||||||||||||||||||
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Semicarbazide-13C,15N2 hydrochloride | 99.86% | Semicarbazide-13C,15N2 (Aminourea-13C,15N2) hydrochloride is the 13C- and 15N-labeled Semicarbazide hydrochloride (HY-Y0470). Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles. | ||||||||||||||||||||
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References
- [1]. Adam Becalski, et al. Semicarbazide Formation in Azodicarbonamide-Treated Flour: A Model Study. J Agric Food Chem. 2004 Sep 8;52(18):5730-4. [Content Brief]
- [2]. Hernandez M, et al. Soluble semicarbazide sensitive amine oxidase (SSAO) catalysis induces apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 2006 Feb;1763(2):164-73. [Content Brief]
- [3]. Takahashi M, et al. Chronic toxicity and carcinogenicity of semicarbazide hydrochloride in Wistar Hannover GALAS rats. Food Chem Toxicol. 2014 Nov;73:84-94. [Content Brief]
- [4]. Takahashi M, et al. Age-related susceptibility to induction of osteochondral and vascular lesions by semicarbazide hydrochloride in rats. Toxicol Pathol. 2010 Jun;38(4):598-605. [Content Brief]
- [5]. Elswaidy N R, et al. The effect of semicarbazide on the thyroid gland of juvenile male albino rat and possibility of recovery: Histological and immunohistochemical study. Egyptian Journal of Histology, 2022, 45(2): 537-547.
- [6]. Alazouny Z M, et al. Harmful Effect of Semicarbazide on the Ovary of Adult Albino Rats and the Possible Reversibility of the Induced Lesions (Biochemical and Histological Study). Egyptian Journal of Histology, 2023, 46(2): 810-821.
- [7]. Mansour A M, et al. Histological Study of the Effect of Semicarbazide on Testicular Seminiferous Tubules of Juvenile Albino Rat. Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2018, 30(1): 27-37.
- [8]. Maranghi F, et al. Effects of the food contaminant semicarbazide following oral administration in juvenile Sprague-Dawley rats. Food Chem Toxicol. 2009 Feb;47(2):472-9. [Content Brief]
- [9]. Huang H Y, et al. Study on semicarbazide-induced oxidative stress and hepatic metabolic damage in SD rats. 2021.
