Aminoguanidine-13C, 15N4
Aminoguanidine-13C,15N4 (Pimagedine-13C,15N4) is the 13C,15N4-labeled Aminoguanidine (HY-W020772). Aminoguanidine is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine has antioxidant properties. Aminoguanidine can be used in the research of diabetic nephropathy.
For research use only. We do not sell to patients.
- CAS No.: 478189-68-3
- Formula: 13CH615N4
- Molecular Weight:79.05
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 478189-68-3
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Molecular Weight 79.05
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Formula 13CH615N4
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SMILES
[15NH2][15NH][13C]([15NH2])=[15NH]
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Synonyms
Pimagedine-13C, 15N4; GER-11free base-13C, 15N4; Aminoguanidinium-13C, 15N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sabuncuoglu S. Antiapoptotic effect of aminoguanidine on doxorubicin-induced apoptosis. Mol Cell Biochem. 2014 Sep;394(1-2):129-35. [Content Brief]
[2]. Chowdhury P. Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line. Ann Clin Lab Sci. 2017 Sep;47(5):572-580. PMID: 29066484. [Content Brief]
[3]. Al-Shabanah OA, et al. Protective effect of aminoguanidine, a nitric oxide synthase inhibitor, against carbon tetrachloride induced hepatotoxicity in mice. Life Sci. 2000;66(3):265-70. [Content Brief]
[4]. Abraham P, et al. Protective effect of aminoguanidine against cyclophosphamide-induced oxidative stress and renal damage in rats. Redox Rep. 2011;16(1):8-14. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aminoguanidine-13C, 15N4 Related Classifications
HY-B1041AS Related Classifications
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