2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. Cholestenone-13C2

Cholestenone-13C2  (Synonyms: 4-Cholesten-3-one-13C2)

Cat. No.: HY-113365S2 Purity: 99.06%
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Cholestenone-13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells.

For research use only. We do not sell to patients.

Cholestenone-<sup>13</sup>C<sub>2</sub>

Cholestenone-13C2 Chemical Structure

CAS No. : 82938-09-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Cholestenone-13C2:

Cholestenone-13C2 Related Antibodies

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Description

Cholestenone-13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholestenone-13C2 Related Antibodies
Molecular Weight

386.62

Formula

C2513C2H44O
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=[13CH][13C](CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 50 mg/mL (129.33 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5865 mL 12.9326 mL 25.8652 mL
5 mM 0.5173 mL 2.5865 mL 5.1730 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.5865 mL 12.9326 mL 25.8652 mL 64.6630 mL
5 mM 0.5173 mL 2.5865 mL 5.1730 mL 12.9326 mL
10 mM 0.2587 mL 1.2933 mL 2.5865 mL 6.4663 mL
15 mM 0.1724 mL 0.8622 mL 1.7243 mL 4.3109 mL
20 mM 0.1293 mL 0.6466 mL 1.2933 mL 3.2331 mL
25 mM 0.1035 mL 0.5173 mL 1.0346 mL 2.5865 mL
30 mM 0.0862 mL 0.4311 mL 0.8622 mL 2.1554 mL
40 mM 0.0647 mL 0.3233 mL 0.6466 mL 1.6166 mL
50 mM 0.0517 mL 0.2587 mL 0.5173 mL 1.2933 mL
60 mM 0.0431 mL 0.2155 mL 0.4311 mL 1.0777 mL
80 mM 0.0323 mL 0.1617 mL 0.3233 mL 0.8083 mL
100 mM 0.0259 mL 0.1293 mL 0.2587 mL 0.6466 mL
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Cholestenone-13C2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholestenone-13C282938-09-84-Cholesten-3-one-13C2Isotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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