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3-Hydroxy Midostaurin-d5 (Synonyms: CGP52421-d5)

Cat. No.: HY-108263S
Handling Instructions

3-Hydroxy Midostaurin-d5 (CGP52421-d5) is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively.

For research use only. We do not sell to patients.

3-Hydroxy Midostaurin-d5 Chemical Structure

3-Hydroxy Midostaurin-d5 Chemical Structure

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Description

3-Hydroxy Midostaurin-d5 (CGP52421-d5) is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

Molecular Weight

591.67

Formula

C₃₅H₂₅D₅N₄O₅

SMILES

O[[email protected]]1NC(C2=C1C(C3=C4C=CC=C3)=C5N4[[email protected]]6(O[[email protected]@H](N7C5=C2C8=C7C=CC=C8)C[[email protected]]([[email protected]]6OC)N(C(C(C([2H])=C9[2H])=C(C([2H])=C9[2H])[2H])=O)C)C)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

3-Hydroxy Midostaurin-d5CGP52421-d5OthersInhibitorinhibitorinhibit

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3-Hydroxy Midostaurin-d5
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HY-108263S
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