Cyclamic Acid-d11
Based on 1 Customer Validation
Cyclamic Acid-d11 is the deuterium labeled Cyclamic acid. Cyclamic acid (Cyclohexylsulfamic acid) is one of the most widely used artificial sweetenersin food and pharmaceuticals.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.90%
- CAS No.: 1215770-73-2
- 화학식: C6H2D11NO3S
- 분자량:190.31
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1215770-73-2
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Unlabeled Cas 100-88-9
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Appearance Solid
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분자량 190.31
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화학식 C6H2D11NO3S
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Color White to off-white
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SMILES
O=S(NC1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])(O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
H2O : 100 mg/mL (525.46 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Leban I, et, al. Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta Crystallogr B. 2007 Jun;63(Pt 3):418-25. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2546 mL | 26.2729 mL | 52.5458 mL | 131.3646 mL |
| 5 mM | 1.0509 mL | 5.2546 mL | 10.5092 mL | 26.2729 mL | |
| 10 mM | 0.5255 mL | 2.6273 mL | 5.2546 mL | 13.1365 mL | |
| 15 mM | 0.3503 mL | 1.7515 mL | 3.5031 mL | 8.7576 mL | |
| 20 mM | 0.2627 mL | 1.3136 mL | 2.6273 mL | 6.5682 mL | |
| 25 mM | 0.2102 mL | 1.0509 mL | 2.1018 mL | 5.2546 mL | |
| 30 mM | 0.1752 mL | 0.8758 mL | 1.7515 mL | 4.3788 mL | |
| 40 mM | 0.1314 mL | 0.6568 mL | 1.3136 mL | 3.2841 mL | |
| 50 mM | 0.1051 mL | 0.5255 mL | 1.0509 mL | 2.6273 mL | |
| 60 mM | 0.0876 mL | 0.4379 mL | 0.8758 mL | 2.1894 mL | |
| 80 mM | 0.0657 mL | 0.3284 mL | 0.6568 mL | 1.6421 mL | |
| 100 mM | 0.0525 mL | 0.2627 mL | 0.5255 mL | 1.3136 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.