p-Tolylmaleimide

Cat. No.: HY-129592: FAQs
Data Sheet SDS COA Handling Instructions

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p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis.

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p-Tolylmaleimide Chemical Structure

CAS No. : 1631-28-3

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
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Description	p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis^[1].
In Vitro	p-Tolylmaleimide inhibits human acute myeloid leukemia cell K562 with IC₅₀s of 24.99 μM (24 h), 6.61 (48 h), and 12.10 (72 h) respectively. p-Tolylmaleimide for inhibits human acute myeloid leukemia cell Jurkat with IC₅₀s of 27.16 μM (24 h), 15.51 (48 h), and 3.94 (72 h) respectively^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. p-Tolylmaleimide Related Antibodies
Molecular Weight	187.19
Formula	C₁₁H₉NO₂
CAS No.	1631-28-3
Appearance	Solid
Color	Light yellow to yellow
SMILES	O=C(C=C1)N(C2=CC=C(C)C=C2)C1=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (272 KB) SDS (555 KB) COA (256 KB) HNMR (128 KB) Handling Instructions (2659 KB)
References	[1]. Machado KE, et al. Apoptotic events induced by maleimides on human acute leukemia cell lines. Chem Res Toxicol. 2013 Dec 16;26(12):1904-16. [Content Brief]

p-Tolylmaleimide Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p-Tolylmaleimide1631-28-3ApoptosisHuman acute myeloid leukemia cellsnaphthalimideInhibitorinhibitorinhibit

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p-Tolylmaleimide

p-Tolylmaleimide Related Antibodies

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