2. Protein Tyrosine Kinase/RTK Anti-infection Autophagy
  3. Bcr-Abl PDGFR c-Kit SARS-CoV Autophagy
  4. Imatinib-d4

Imatinib-d4  (Synonyms: STI571 d4; CGP-57148B d4)

Cat. No.: HY-15463S1 Purity: 99.97%
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Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].

For research use only. We do not sell to patients.

Imatinib-d<sub>4</sub> Chemical Structure

Imatinib-d4 Chemical Structure

CAS No. : 1134803-16-9

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Based on 1 publication(s) in Google Scholar

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Description

Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].

Molecular Weight

497.63

Formula

C29H27D4N7O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=C([2H])C([2H])=C(CN5CCN(C)CC5)C([2H])=C4[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.97%

COA (246 KB) HNMR (116 KB) RP-HPLC (375 KB) LCMS (95 KB)

Handling Instructions (2659 KB)
References
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Imatinib-d4 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Imatinib-d41134803-16-9STI571 d4CGP-57148B d4Bcr-AblPDGFRc-KitSARS-CoVAutophagyPlatelet-derived growth factor receptorSCFRCD117SARS coronavirusdeuteriumImatinibtyrosinekinasesautophosphorylationInhibitorinhibitorinhibit

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