Cytidine-5'-triphosphate-15N3,d14 dilithium
Cytidine-5'-triphosphate-15N3,d14 (Cytidine triphosphate-15N3,d14 dilithium; 5'-CTP-15N3,d14) dilithium is deuterium and 15N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
For research use only. We do not sell to patients.
- Formula: C9D14Li215N3O14P3
- Molecular Weight:512.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 65-47-4
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Molecular Weight 512.09
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Formula C9D14Li215N3O14P3
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SMILES
O=P(O[2H])(O[Li])OP(OP(OC([2H])([2H])[C@]1([2H])[C@](O[2H])([2H])[C@@](O[2H])([2H])[C@@]([15N]2C([15N]=C([15N]([2H])[2H])C([2H])=C2[2H])=O)([2H])O1)(O[2H])=O)(O[Li])=O
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Synonyms
Cytidine triphosphate-15N3,d14 dilithium; 5'-CTP-15N3,d14 dilithium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cytidine-5'-triphosphate-15N3,d14 dilithium Related Classifications
HY-125818S5 Related Classifications
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Keywords
- Cytidine-5'-triphosphate-15N3,d14 dilithium
- Cytidine triphosphate-15N3,d14 dilithium
- 5'-CTP-15N3,d14 dilithium
- Isotope-Labeled Compounds
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- Endogenous Metabolite
- nucleoside triphosphate
- building block
- nucleic acid
- pyrimidine biosynthetic
- Cytidine triphosphate synthase
- T. gondii
- Inhibitor
- inhibitor
- inhibit