Cytidine-5′-triphosphate-d14 disodium
Based on 1 Customer Validation
Cytidine-5′-triphosphate-d14 disodium is the deuterium labeled Cytidine-5'-triphosphate. Cytidine 5′-triphosphate (Cytidine triphosphate;5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
For research use only. We do not sell to patients.
- Purity: 98.00%
- Formula: C9D14N3Na2O14P3
- Molecular Weight:541.21
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Storage:
Solution, -20°C, protect from light, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 65-47-4
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Appearance Liquid
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Molecular Weight 541.21
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Formula C9D14N3Na2O14P3
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Color Colorless to light yellow
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SMILES
O=P(O[2H])(O[Na])OP(OP(OC([2H])([2H])[C@@]1([2H])[C@](O[2H])([2H])[C@@](O[2H])([2H])[C@](N2C(N=C(N([2H])[2H])C([2H])=C2[2H])=O)([2H])O1)(O[2H])=O)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, protect from light, 2 years
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cytidine-5′-triphosphate-d14 disodium Related Classifications
HY-125818S1 Related Classifications
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