Diethylstilbestrol-d8
Based on 1 Customer Validation
Diethylstilbestrol-d8 is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 91318-10-4
- Formula: C18H12D8O2
- Molecular Weight:276.40
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 91318-10-4
-
Unlabeled Cas 56-53-1
-
Appearance Solid
-
Molecular Weight 276.40
-
Formula C18H12D8O2
-
Color White to off-white
-
SMILES
CC([2H])([2H])/C(C1=CC([2H])=C(C([2H])=C1)O)=C(C2=CC([2H])=C(C([2H])=C2)O)/C([2H])([2H])C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (180.90 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
-
Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Troisi, R., et al., Medical conditions among adult offspring prenatally exposed to diethylstilbestrol. Epidemiology, 2013. 24(3): p. 430-8. [Content Brief]
[3]. Kebir, O. and M.O. Krebs, Diethylstilbestrol and risk of psychiatric disorders: a critical review and new insights. World J Biol Psychiatry, 2012. 13(2): p. 84-95. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6179 mL | 18.0897 mL | 36.1795 mL | 90.4486 mL |
| 5 mM | 0.7236 mL | 3.6179 mL | 7.2359 mL | 18.0897 mL | |
| 10 mM | 0.3618 mL | 1.8090 mL | 3.6179 mL | 9.0449 mL | |
| 15 mM | 0.2412 mL | 1.2060 mL | 2.4120 mL | 6.0299 mL | |
| 20 mM | 0.1809 mL | 0.9045 mL | 1.8090 mL | 4.5224 mL | |
| 25 mM | 0.1447 mL | 0.7236 mL | 1.4472 mL | 3.6179 mL | |
| 30 mM | 0.1206 mL | 0.6030 mL | 1.2060 mL | 3.0150 mL | |
| 40 mM | 0.0904 mL | 0.4522 mL | 0.9045 mL | 2.2612 mL | |
| 50 mM | 0.0724 mL | 0.3618 mL | 0.7236 mL | 1.8090 mL | |
| 60 mM | 0.0603 mL | 0.3015 mL | 0.6030 mL | 1.5075 mL | |
| 80 mM | 0.0452 mL | 0.2261 mL | 0.4522 mL | 1.1306 mL | |
| 100 mM | 0.0362 mL | 0.1809 mL | 0.3618 mL | 0.9045 mL |
Diethylstilbestrol-d8 Related Classifications
HY-14598S Related Classifications
Powered by Bioz