Deltamethrin-d5
Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.
For research use only. We do not sell to patients.
- CAS No.: 2140301-99-9
- Formula: C22H14D5Br2NO3
- Molecular Weight:510.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2140301-99-9
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Unlabeled Cas 52918-63-5
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Molecular Weight 510.23
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Formula C22H14D5Br2NO3
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SMILES
N#C[C@H](C1=CC(OC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=CC=C1)OC([C@@H]3[C@@H](C3(C)C)/C=C(Br)\Br)=O
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Synonyms
Decamethrin-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kavlock R, et al. Toxicity studies with decamethrin, a synthetic pyrethroid insecticide. J Environ Pathol Toxicol. 1979;2(3):751-765.;Ray DE. An EEG investigation of decamethrin-induced choreoathetosis in the rat. Exp Brain Res. 1980;38(2):221-227. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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