Octenyl succinic anhydride
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Octenyl succinic anhydride is a versatile chemical intermediate. Octenyl succinic anhydride can undergo esterification with polysaccharides such as starch and Inulin (HY-N7075). Octenyl succinic anhydride affects the intermolecular interactions on the outer surfaces of two starch granules by altering the molecular surface structure. Octenyl succinic anhydride modifies the properties of polysaccharides. Octenyl succinic anhydride can be used for starch esterification to produce OS-starch, an amphiphilic hydrocolloid.
For research use only. We do not sell to patients.
- Purity : 99.69%
- CAS No.: 26680-54-6
- Formula: C12H18O3
- Molecular Weight:210.27
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Octenyl succinic anhydride undergoes esterification with polysaccharides such as starch and Inulin (HY-N7075)[1][2][3].
Octenyl succinic anhydride affects the intermolecular interactions on the outer surfaces of two starch granules by altering the molecular surface structure[1][2][3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 26680-54-6
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Appearance Liquid (Density: 1 g/cm3)
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Molecular Weight 210.27
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Formula C12H18O3
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Color Colorless to light yellow
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SMILES
O=C(C(/C=C/CCCCCC)C1)OC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (475.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.89 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (11.89 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Gao W, et al. Synthetic mechanism of octenyl succinic anhydride modified corn starch based on shells separation pretreatment. Int J Biol Macromol. 2021;172:483-489. [Content Brief]
[2]. Zhang X, et al. Preparation, characterization and antibacterial activity of octenyl succinic anhydride modified inulin. Int J Biol Macromol. 2015;78:79-86. [Content Brief]
[3]. Sweedman MC, et al. Structure and physicochemical properties of octenyl succinic anhydride modified starches: a review. Carbohydr Polym. 2013;92(1):905-920. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.7558 mL | 23.7790 mL | 47.5579 mL | 118.8948 mL |
| 5 mM | 0.9512 mL | 4.7558 mL | 9.5116 mL | 23.7790 mL | |
| 10 mM | 0.4756 mL | 2.3779 mL | 4.7558 mL | 11.8895 mL | |
| 15 mM | 0.3171 mL | 1.5853 mL | 3.1705 mL | 7.9263 mL | |
| 20 mM | 0.2378 mL | 1.1889 mL | 2.3779 mL | 5.9447 mL | |
| 25 mM | 0.1902 mL | 0.9512 mL | 1.9023 mL | 4.7558 mL | |
| 30 mM | 0.1585 mL | 0.7926 mL | 1.5853 mL | 3.9632 mL | |
| 40 mM | 0.1189 mL | 0.5945 mL | 1.1889 mL | 2.9724 mL | |
| 50 mM | 0.0951 mL | 0.4756 mL | 0.9512 mL | 2.3779 mL | |
| 60 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.9816 mL | |
| 80 mM | 0.0594 mL | 0.2972 mL | 0.5945 mL | 1.4862 mL | |
| 100 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1889 mL |
Octenyl succinic anhydride Related Classifications
HY-145942 Related Classifications
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