3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt
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3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt (PAPS tetralithium salt) is the cosubstrate and the source of sulfonic acid groups in sulfation reactions. 3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt is important for maintaining sulfation balance in living organisms.
For research use only. We do not sell to patients.
- Purity: 92.0%
- CAS No.: 102029-54-9
- Formula: C10H11Li4N5O13P2S
- Molecular Weight:531.00
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Storage:
-80°C
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3'-Phosphoadenosine 5'-phosphosulfate tetralithium salt is the sulfuric acid group donor in the sulfation reaction. Its availability, rather than the activity of the sulfation enzyme itself, is the main limiting factor for the capacity of sulfation reactions in the body[1][3].
3′-phosphoadenosine 5′-phosphosulfate tetralithium salt is involved in the transport of membrane vesicles through active transport: it is accomplished by relying on specific PAPS transport proteins (PAPST)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 102029-54-9
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Appearance Solid
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Molecular Weight 531.00
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Formula C10H11Li4N5O13P2S
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Color White to off-white
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SMILES
O=P(O[Li])(O[Li])O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COP(OS(=O)(O[Li])=O)(O[Li])=O
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Synonyms
PAPS tetralithium salt
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Shipping
Shipping with dry ice.
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Storage
-80°C
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Klaassen CD, et al., Sulfation and sulfotransferases 5: the importance of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) in the regulation of sulfation. FASEB J. 1997 May;11(6):404-18. [Content Brief]
[2]. Nishihara S. Assay of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) transport activity. 2021 Aug 11 [updated 2022 Apr 30]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. [Content Brief]
[3]. Vargas F, et al. 3'-Phosphoadenosine 5'-phosphosulfate biosynthesis and the sulfation of cholecystokinin by the tyrosylprotein-sulfotransferase in rat brain tissue. Chem Biol Interact. 1994 Jun;92(1-3):281-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt Related Classifications
HY-157424 Related Classifications
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