Dodecylamine-d25
Dodecylamine-d25 (Laurylamine-d25) is the deuterated-labeled Dodecylamine (HY-B1638). Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis.
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- CAS. Nr.: 1219802-72-8
- Formel: C12H2D25N
- Molecular Weight:210.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1219802-72-8
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Unlabeled CAS 124-22-1
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Molecular Weight 210.50
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Formel C12H2D25N
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SMILES
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N
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Synonyms
Laurylamine-d25
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Keywords
- Dodecylamine-d25
- 1219802-72-8
- Laurylamine-d25
- Isotope-Labeled Compounds
- Drug Intermediate
- Biochemical Assay Reagents
- CD36
- DNA binding
- HeLa cells
- apoptosis
- cationic nanoparticles
- class B ligand
- electrostatic interactions
- extracellular CD36 ligand-recognition segment
- self-assembly
- van der Waals interactions
- Inhibitor
- inhibitor
- inhibit