124-22-1
Chemical Structure
Dodecylamine
Synonym(s): Laurylamine
- CAS No.: 124-22-1
- Formula:C12H27N
- Molecular Weight:185.36
IUPAC Name: dodecan-1-amine
InChIKey: JRBPAEWTRLWTQC-UHFFFAOYSA-N
SMILES: NCCCCCCCCCCCC
Biological Activity: Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dodecylamine | 98.77% | Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis. | ||||||||||||||||||||
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Dodecylamine-d25 | Dodecylamine-d25 (Laurylamine-d25) is the deuterated-labeled Dodecylamine (HY-B1638). Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis. | |||||||||||||||||||||
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References
- [1]. Saha A, et al. Fatty-amine-conjugated cationic bovine serum albumin nanoparticles for target-specific hydrophobic drug delivery. ACS Applied Nano Materials. 2019 May 8;2(6):3671-83.
- [2]. Tsuzuki S, et al. Fatty amines and 1-monoglycerides with cytotoxic activity serve as ligands for a multipurpose receptor CD36. Biomedical research (Tokyo, Japan). 2025;46(5):189-202. [Content Brief]
- [3]. Nagaraj K, et al. Pharmaceutical evaluation of cis-[co (trien)(4-CNP)(C₁₂H₂₅NH₂)] 3+: A metallo-surfactant with DNA/tRNA affinity and broad-spectrum bioactivity. Journal of Molecular Liquids. 2025 Oct 1;435:128173.
