Venlafaxine-d6 hydrochloride
Based on 1 Customer Validation
Venlafaxine-d6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant.
For research use only. We do not sell to patients.
- Purity: 98.18%
- CAS No.: 1062606-12-5
- Formula: C17H22D6ClNO2
- Molecular Weight:319.90
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B0196A
Venlafaxine hydrochloride
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HY-B1272
Desipramine hydrochloride
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HY-B0161A
Duloxetine hydrochloride
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HY-B1287
Citalopram hydrobromide
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HY-B1287R
Citalopram hydrobromide (Standard)
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HY-B0196AR
Venlafaxine hydrochloride (Standard)
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HY-B1272R
Desipramine hydrochloride (Standard)
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HY-110029
Paroxetine maleate
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HY-B0161AR
Duloxetine hydrochloride (Standard)
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HY-B0478
Trazodone hydrochloride
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HY-B0478R
Trazodone hydrochloride (Standard)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1062606-12-5
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Unlabeled Cas 99300-78-4
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Appearance Solid
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Molecular Weight 319.90
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Formula C17H22D6ClNO2
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Color White to off-white
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SMILES
OC1(C(C2=CC=C(OC)C=C2)CN(C([2H])([2H])[2H])C([2H])([2H])[2H])CCCCC1.[H]Cl
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Synonyms
Wy 45030-d6 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 10 mg/mL (31.26 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80. [Content Brief]
[3]. Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121(1-2):70-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1260 mL | 15.6299 mL | 31.2598 mL | 78.1494 mL |
| 5 mM | 0.6252 mL | 3.1260 mL | 6.2520 mL | 15.6299 mL | |
| 10 mM | 0.3126 mL | 1.5630 mL | 3.1260 mL | 7.8149 mL | |
| 15 mM | 0.2084 mL | 1.0420 mL | 2.0840 mL | 5.2100 mL | |
| 20 mM | 0.1563 mL | 0.7815 mL | 1.5630 mL | 3.9075 mL | |
| 25 mM | 0.1250 mL | 0.6252 mL | 1.2504 mL | 3.1260 mL | |
| 30 mM | 0.1042 mL | 0.5210 mL | 1.0420 mL | 2.6050 mL |
Venlafaxine-d6 hydrochloride Related Classifications
HY-B0196AS1 Related Classifications
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