2. Neuronal Signaling
  3. Serotonin Transporter
  4. Venlafaxine-d6 hydrochloride

Venlafaxine-d6 hydrochloride  (Synonyms: Wy 45030-d6 (hydrochloride))

Cat. No.: HY-B0196AS1 Purity: 98.18%
COA Handling Instructions

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Venlafaxine-d6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

For research use only. We do not sell to patients.

Venlafaxine-d<sub>6</sub> hydrochloride Chemical Structure

Venlafaxine-d6 hydrochloride Chemical Structure

CAS No. : 1062606-12-5

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1 mg USD 90 In-stock
5 mg USD 320 In-stock
10 mg USD 540 In-stock
25 mg USD 1080 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Venlafaxine-d6 hydrochloride:

Venlafaxine-d6 hydrochloride Related Antibodies

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Description

Venlafaxine-d6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Venlafaxine-d6 hydrochloride Related Antibodies
Molecular Weight

319.90

Formula

C17H22D6ClNO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1(C(C2=CC=C(OC)C=C2)CN(C([2H])([2H])[2H])C([2H])([2H])[2H])CCCCC1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (31.26 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1260 mL 15.6299 mL 31.2598 mL
5 mM 0.6252 mL 3.1260 mL 6.2520 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.18%

COA (256 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1260 mL 15.6299 mL 31.2598 mL 78.1494 mL
5 mM 0.6252 mL 3.1260 mL 6.2520 mL 15.6299 mL
10 mM 0.3126 mL 1.5630 mL 3.1260 mL 7.8149 mL
15 mM 0.2084 mL 1.0420 mL 2.0840 mL 5.2100 mL
20 mM 0.1563 mL 0.7815 mL 1.5630 mL 3.9075 mL
25 mM 0.1250 mL 0.6252 mL 1.2504 mL 3.1260 mL
30 mM 0.1042 mL 0.5210 mL 1.0420 mL 2.6050 mL
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Venlafaxine-d6 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Venlafaxine-d61062606-12-5Wy 45030-d6Serotonin Transporter5-HTTSERTSLC6A4Inhibitorinhibitorinhibit

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