1. Immunology/Inflammation
    Anti-infection
  2. Toll-like Receptor (TLR)
    HCV
  3. Resiquimod-d5

Resiquimod-d5 (Synonyms: R848-d5; S28463-d5)

Cat. No.: HY-13740S Purity: 98.46%
Handling Instructions

Resiquimod-d5 (R848-d5) is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

For research use only. We do not sell to patients.

Resiquimod-d5 Chemical Structure

Resiquimod-d5 Chemical Structure

CAS No. : 2252319-44-9

Size Price Stock Quantity
5 mg USD 640 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Resiquimod-d5 (R848-d5) is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].

Molecular Weight

319.41

Formula

C₁₇H₁₇D₅N₄O₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (156.54 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1308 mL 15.6539 mL 31.3077 mL
5 mM 0.6262 mL 3.1308 mL 6.2615 mL
10 mM 0.3131 mL 1.5654 mL 3.1308 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.83 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.83 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Resiquimod-d5
Cat. No.:
HY-13740S
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