2252319-44-9
2252319-44-9
Chemical Structure
Resiquimod-d5
Synonym(s): R848-d5;S28463-d5
- CAS No.: 2252319-44-9
- Formula:C17H17D5N4O2
- Molecular Weight:319.41
IUPAC Name: 1-(4-amino-2-((ethoxy-d5)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
InChIKey: BXNMTOQRYBFHNZ-SGEUAGPISA-N
SMILES: CC(C)(O)CN1C2=C(N=C1COC([2H])([2H])C([2H])([2H])[2H])C(N)=NC3=CC=CC=C23
Biological Activity: Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Resiquimod-d5 | 98.33% | Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. | ||||||||||||||||||||
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Resiquimod (GMP) | Resiquimod (R848) (GMP) is Resiquimod (HY-13740) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist. Resiquimod (GMP) can induce human mMDSC to mature into inflammatory macrophages. | |||||||||||||||||||||
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Resiquimod (Standard) | ≥98% | Resiquimod (Standard) is the analytical standard of Resiquimod. This product is intended for research and analytical applications. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. | ||||||||||||||||||||
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Resiquimod | 99.87% | Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. | ||||||||||||||||||||
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References
- [1]. Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32. [Content Brief]
- [2]. Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20. [Content Brief]
