2. Metabolic Enzyme/Protease PI3K/Akt/mTOR Epigenetics
  3. ATP Citrate Lyase AMPK
  4. Bempedoic acid-d4

Bempedoic acid-d4  (Synonyms: ETC-1002-d4; ESP-55016-d4)

Cat. No.: HY-12357S2 Purity: ≥98.0%
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Bempedoic acid-d4 is the deuterium labeled Bempedoic acid. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. Bempedoic acid (ETC-1002) activates AMPK[1][2].

For research use only. We do not sell to patients.

Bempedoic acid-d<sub>4</sub> Chemical Structure

Bempedoic acid-d4 Chemical Structure

CAS No. : 2408131-70-2

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1 mg USD 450 In-stock
5 mg USD 1800 In-stock
10 mg USD 2850 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Bempedoic acid-d4:

Bempedoic acid-d4 Related Antibodies

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

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Description

Bempedoic acid-d4 is the deuterium labeled Bempedoic acid. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. Bempedoic acid (ETC-1002) activates AMPK[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bempedoic acid-d4 Related Antibodies
Molecular Weight

348.51

Formula

C19H32D4O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C(C)(C)CCCCC([2H])([2H])C(O)C([2H])([2H])CCCCC(C)(C)C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (143.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8694 mL 14.3468 mL 28.6936 mL
5 mM 0.5739 mL 2.8694 mL 5.7387 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8694 mL 14.3468 mL 28.6936 mL 71.7340 mL
5 mM 0.5739 mL 2.8694 mL 5.7387 mL 14.3468 mL
10 mM 0.2869 mL 1.4347 mL 2.8694 mL 7.1734 mL
15 mM 0.1913 mL 0.9565 mL 1.9129 mL 4.7823 mL
20 mM 0.1435 mL 0.7173 mL 1.4347 mL 3.5867 mL
25 mM 0.1148 mL 0.5739 mL 1.1477 mL 2.8694 mL
30 mM 0.0956 mL 0.4782 mL 0.9565 mL 2.3911 mL
40 mM 0.0717 mL 0.3587 mL 0.7173 mL 1.7933 mL
50 mM 0.0574 mL 0.2869 mL 0.5739 mL 1.4347 mL
60 mM 0.0478 mL 0.2391 mL 0.4782 mL 1.1956 mL
80 mM 0.0359 mL 0.1793 mL 0.3587 mL 0.8967 mL
100 mM 0.0287 mL 0.1435 mL 0.2869 mL 0.7173 mL
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Bempedoic acid-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bempedoic acid-d42408131-70-2ETC-1002-d4ESP-55016-d4ATP Citrate LyaseAMPKACLYAMP-activated protein kinaseInhibitorinhibitorinhibit

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