Aliskiren-d6 hemifumarate
Aliskiren-d6 (hemifumarate) is a deuterium labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor with an IC50 of 1.5 nM.
For research use only. We do not sell to patients.
- Formula: C32H49D6N3O8
- Molecular Weight:615.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 1.5 nM (renin)[1]
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 173334-58-2
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Molecular Weight 615.83
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Formula C32H49D6N3O8
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SMILES
O=C(NCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(N)=O)[C@H](C(C)C)C[C@H](O)[C@@H](N)C[C@@H](C(C)C)CC1=CC(OCCCOC)=C(OC)C=C1.O=C(O)/C=C/C(O)=O.[1/2]
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Synonyms
CGP 60536 D6 hemifumarate; CGP60536B D6 hemifumarate; SPP 100 D6 hemifumarate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yuji Nakamura, et al. Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor. ACS Med. Chem. Lett., 2012, 3 (9), pp 754-758. [Content Brief]
[2]. Buczko W, et al. Pharmacokinetics and pharmacodynamics of aliskiren, an oral direct renin inhibitor. Pharmacol Rep. 2008 Sep-Oct;60(5):623-31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aliskiren-d6 hemifumarate Related Classifications
HY-12177S Related Classifications
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