2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. D-Alanine-d7

D-Alanine-d7  (Synonyms: (R)-Alanine-d7; Ba 2776-d7; D-α-Alanine-d7)

Cat. No.: HY-41700S3 Purity: ≥99.0%
COA Handling Instructions

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D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

For research use only. We do not sell to patients.

D-Alanine-d<sub>7</sub> Chemical Structure

D-Alanine-d7 Chemical Structure

CAS No. : 2483831-62-3

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1 mg USD 40 In-stock
5 mg USD 138 In-stock
10 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of D-Alanine-d7:

D-Alanine-d7 Related Antibodies

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Description

D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

D-Alanine-d7 Related Antibodies
Molecular Weight

96.14

Formula

C3D7NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]OC([C@@](N([2H])[2H])([2H])C([2H])([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 165 mg/mL (1716.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.4015 mL 52.0075 mL 104.0150 mL
5 mM 2.0803 mL 10.4015 mL 20.8030 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 10.4015 mL 52.0075 mL 104.0150 mL 260.0374 mL
5 mM 2.0803 mL 10.4015 mL 20.8030 mL 52.0075 mL
10 mM 1.0401 mL 5.2007 mL 10.4015 mL 26.0037 mL
15 mM 0.6934 mL 3.4672 mL 6.9343 mL 17.3358 mL
20 mM 0.5201 mL 2.6004 mL 5.2007 mL 13.0019 mL
25 mM 0.4161 mL 2.0803 mL 4.1606 mL 10.4015 mL
30 mM 0.3467 mL 1.7336 mL 3.4672 mL 8.6679 mL
40 mM 0.2600 mL 1.3002 mL 2.6004 mL 6.5009 mL
50 mM 0.2080 mL 1.0401 mL 2.0803 mL 5.2007 mL
60 mM 0.1734 mL 0.8668 mL 1.7336 mL 4.3340 mL
80 mM 0.1300 mL 0.6501 mL 1.3002 mL 3.2505 mL
100 mM 0.1040 mL 0.5201 mL 1.0401 mL 2.6004 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Alanine-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Alanine-d72483831-62-3(R)-Alanine-d7Ba 2776-d7D-α-Alanine-d7Endogenous MetaboliteInhibitorinhibitorinhibit

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