Nonanoic acid-d4
Based on 1 Customer Validation
Nonanoic acid (Pelargonic acid)-d4 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 1219795-27-3
- Formula: C9H14D4O2
- Molecular Weight:162.26
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219795-27-3
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Unlabeled Cas 112-05-0
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Appearance Liquid
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Molecular Weight 162.26
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Formula C9H14D4O2
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Color Colorless to light yellow
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SMILES
CCC([2H])([2H])C([2H])([2H])CCCCC(O)=O
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Synonyms
Pelargonic acid-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (616.29 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Wang J, et al. Caprylic acid and nonanoic acid upregulate endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.Int Immunopharmacol. 2018 Dec;65:303-311. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1629 mL | 30.8147 mL | 61.6295 mL | 154.0737 mL |
| 5 mM | 1.2326 mL | 6.1629 mL | 12.3259 mL | 30.8147 mL | |
| 10 mM | 0.6163 mL | 3.0815 mL | 6.1629 mL | 15.4074 mL | |
| 15 mM | 0.4109 mL | 2.0543 mL | 4.1086 mL | 10.2716 mL | |
| 20 mM | 0.3081 mL | 1.5407 mL | 3.0815 mL | 7.7037 mL | |
| 25 mM | 0.2465 mL | 1.2326 mL | 2.4652 mL | 6.1629 mL | |
| 30 mM | 0.2054 mL | 1.0272 mL | 2.0543 mL | 5.1358 mL | |
| 40 mM | 0.1541 mL | 0.7704 mL | 1.5407 mL | 3.8518 mL | |
| 50 mM | 0.1233 mL | 0.6163 mL | 1.2326 mL | 3.0815 mL | |
| 60 mM | 0.1027 mL | 0.5136 mL | 1.0272 mL | 2.5679 mL | |
| 80 mM | 0.0770 mL | 0.3852 mL | 0.7704 mL | 1.9259 mL | |
| 100 mM | 0.0616 mL | 0.3081 mL | 0.6163 mL | 1.5407 mL |
Nonanoic acid-d4 Related Classifications
HY-N7057S2 Related Classifications
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