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Cat. No.: HY-N5134S1

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5'-Guanylic acid-¹³C₁₀ dilithium

Name: 5'-Guanylic acid-13C10 dilithium
Brand: MedChemExpress
SKU: HY-N5134S1
Availability: PreOrder

(Synonyms: 5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10 dilithium)

5'-Guanylic acid-¹³C₁₀ (5'-GMP-¹³C₁₀ dilithium; 5'-guanosine monophosphate-¹³C₁₀) dilithium is ¹³C-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

For research use only. We do not sell to patients.

Formula: ¹³C₁₀H₁₂Li₂N₅O₈P
Molecular Weight:385.01

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

5'-Guanylic acid-¹³C₁₀ dilithium Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 85-32-5
Molecular Weight 385.01
Formula ¹³C₁₀H₁₂Li₂N₅O₈P
SMILES

O=P(O[Li])(O[Li])O[13CH2][13C@H]1O[13C@@H](N2[13C](N=[13C](N)N[13C]3=O)=[13C]3N=[13CH]2)[13C@H](O)[13C@@H]1O
Synonyms

5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10 dilithium
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

5'-Guanylic acid-¹³C₁₀ dilithium

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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5'-Guanylic acid-13C10 dilithium

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

5'-Guanylic acid-13C10 dilithium Related Classifications

HY-N5134S1 Related Classifications

Bioz

5'-Guanylic acid-¹³C₁₀ dilithium

5'-Guanylic acid-¹³C₁₀ dilithium Related Classifications