1. Metabolic Enzyme/Protease
    Apoptosis
  2. Dipeptidyl Peptidase
    Ferroptosis
    Apoptosis
  3. Vildagliptin-d3

Vildagliptin-d3 (Synonyms: LAF237-d3; NVP-LAF 237-d3)

Cat. No.: HY-14291S
Handling Instructions

Vildagliptin-d3 (LAF237-d3) is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

For research use only. We do not sell to patients.

Vildagliptin-d3 Chemical Structure

Vildagliptin-d3 Chemical Structure

CAS No. : 1217546-82-1

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Description

Vildagliptin-d3 (LAF237-d3) is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

306.42

Formula

C₁₇H₂₂D₃N₃O₂

CAS No.
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