Quinoline-2-carboxylic acid-d6
Quinoline-2-carboxylic acid-d6 is the deuterium labeled Quinoline-2-carboxylic acid (HY-W002011). Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds.
For research use only. We do not sell to patients.
- CAS No.: 1219802-18-2
- Formula: C10HD6NO2
- Molecular Weight:179.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219802-18-2
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Unlabeled Cas 93-10-7
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Molecular Weight 179.21
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Formula C10HD6NO2
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SMILES
OC(C1=NC2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[3]. Yang R, et al., Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line. Appl Biochem Biotechnol. 2023 Aug;195(8):4818-4831. [Content Brief]
[4]. Wade JJ, et al., Antiallergic activity of tetracyclic derivatives of quinoline-2-carboxylic acid. 2. Some benzothienoquinolinecarboxylic acids. J Med Chem. 1978 Sep;21(9):941-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Quinoline-2-carboxylic acid-d6 Related Classifications
HY-W002011S Related Classifications
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