Zanubrutinib-d5
Based on 1 Customer Validation
Zanubrutinib-d5 is deuterium labeled Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (Btk) inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 3027617-37-1
- Formula: C27H24D5N5O3
- Molecular Weight:476.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3027617-37-1
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Unlabeled Cas 1633350-06-7
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Appearance Solid
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Molecular Weight 476.58
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Formula C27H24D5N5O3
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Color White to off-white
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SMILES
NC(C1=C2N(N=C1C3=CC=C(OC4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])C=C3)[C@H](C5CCN(C(C=C)=O)CC5)CCN2)=O
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Synonyms
BGB-3111-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 30 mg/mL (62.95 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0983 mL | 10.4914 mL | 20.9828 mL | 52.4571 mL |
| 5 mM | 0.4197 mL | 2.0983 mL | 4.1966 mL | 10.4914 mL | |
| 10 mM | 0.2098 mL | 1.0491 mL | 2.0983 mL | 5.2457 mL | |
| 15 mM | 0.1399 mL | 0.6994 mL | 1.3989 mL | 3.4971 mL | |
| 20 mM | 0.1049 mL | 0.5246 mL | 1.0491 mL | 2.6229 mL | |
| 25 mM | 0.0839 mL | 0.4197 mL | 0.8393 mL | 2.0983 mL | |
| 30 mM | 0.0699 mL | 0.3497 mL | 0.6994 mL | 1.7486 mL | |
| 40 mM | 0.0525 mL | 0.2623 mL | 0.5246 mL | 1.3114 mL | |
| 50 mM | 0.0420 mL | 0.2098 mL | 0.4197 mL | 1.0491 mL | |
| 60 mM | 0.0350 mL | 0.1749 mL | 0.3497 mL | 0.8743 mL |