1633350-06-7
1633350-06-7
Chemical Structure
(±)-Zanubrutinib
Synonym(s): (±)-BGB-3111
- CAS No.: 1633350-06-7
- Formula:C27H29N5O3
- Molecular Weight:471.55
IUPAC Name: 7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: RNOAOAWBMHREKO-UHFFFAOYSA-N
SMILES: NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)C(C5CCN(C(C=C)=O)CC5)CCN2)=O
Biological Activity: (±)-Zanubrutinib ((±)-BGB-3111) is the racemate of Zanubrutinib (HY-101474A). (±)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.63 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(±)-Zanubrutinib | 99.41% | (±)-Zanubrutinib ((±)-BGB-3111) is the racemate of Zanubrutinib (HY-101474A). (±)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.63 nM. | ||||||||||||||||||||
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(±)-Zanubrutinib (Standard) | ≥98% | (±)-Zanubrutinib (Standard) is the analytical standard of (±)-Zanubrutinib (HY-101474). This product is intended for research and analytical applications. (±)-Zanubrutinib ((±)-BGB-3111) is the racemate of Zanubrutinib (HY-101474A). (±)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.63 nM. | ||||||||||||||||||||
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Zanubrutinib-d5 | 99.0% | Zanubrutinib-d5 is deuterium labeled Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (Btk) inhibitor. | ||||||||||||||||||||
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References
