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Cat. No.: HY-101474R

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(±)-Zanubrutinib (Standard)

Name: (±)-Zanubrutinib (Standard)
Brand: MedChemExpress
SKU: HY-101474R
Availability: PreOrder

(Synonyms: (±)-BGB-3111 (Standard))

(±)-Zanubrutinib (Standard) is the analytical standard of (±)-Zanubrutinib (HY-101474). This product is intended for research and analytical applications. (±)-Zanubrutinib ((±)-BGB-3111) is the racemate of Zanubrutinib (HY-101474A). (±)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.63 nM.

For research use only. We do not sell to patients.

CAS No.: 1633350-06-7
Formula: C₂₇H₂₉N₅O₃
Molecular Weight:471.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(±)-Zanubrutinib (Standard) Chemical Structure

CAS No.: 1633350-06-7

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1633350-06-7
Molecular Weight 471.55
Formula C₂₇H₂₉N₅O₃
SMILES

NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)C(C5CCN(C(C=C)=O)CC5)CCN2)=O
Synonyms

(±)-BGB-3111 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Na L, et al. BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2597. doi:10.1158/1538-7445.AM2015-2597

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(±)-Zanubrutinib (Standard)

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