Dapagliflozin-d5
Based on 1 Customer Validation
Dapagliflozin-d5 is a deuterium labeled Dapagliflozin (HY-10450). Dapagliflozin is a competitive SGLT2 inhibitor.
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 1204219-80-6
- Formula: C21H20D5ClO6
- Molecular Weight:413.90
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SGLT2 |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1204219-80-6
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Unlabeled Cas 461432-26-8
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Appearance Solid
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Molecular Weight 413.90
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Formula C21H20D5ClO6
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Color White to off-white
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SMILES
O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)OC([2H])([2H])C([2H])([2H])[2H])=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)O)CO
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Synonyms
BMS-512148-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : ≥ 30 mg/mL (72.48 mM)
Ethanol : ≥ 30 mg/mL (72.48 mM)
DMSO : ≥ 30 mg/mL (72.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMF / Ethanol / DMSO | 1 mM | 2.4160 mL | 12.0802 mL | 24.1604 mL | 60.4011 mL |
| 5 mM | 0.4832 mL | 2.4160 mL | 4.8321 mL | 12.0802 mL | |
| 10 mM | 0.2416 mL | 1.2080 mL | 2.4160 mL | 6.0401 mL | |
| 15 mM | 0.1611 mL | 0.8053 mL | 1.6107 mL | 4.0267 mL | |
| 20 mM | 0.1208 mL | 0.6040 mL | 1.2080 mL | 3.0201 mL | |
| 25 mM | 0.0966 mL | 0.4832 mL | 0.9664 mL | 2.4160 mL | |
| 30 mM | 0.0805 mL | 0.4027 mL | 0.8053 mL | 2.0134 mL | |
| 40 mM | 0.0604 mL | 0.3020 mL | 0.6040 mL | 1.5100 mL | |
| 50 mM | 0.0483 mL | 0.2416 mL | 0.4832 mL | 1.2080 mL | |
| 60 mM | 0.0403 mL | 0.2013 mL | 0.4027 mL | 1.0067 mL |
Dapagliflozin-d5 Related Classifications
HY-10450S Related Classifications
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