1. Anti-infection
    Cell Cycle/DNA Damage
  2. CMV
    HSV
    Antibiotic
    Nucleoside Antimetabolite/Analog
  3. Ganciclovir-d5

Ganciclovir-d5 (Synonyms: BW 759-d5; 2'-Nor-2'-deoxyguanosine-d5)

Cat. No.: HY-13637S
Handling Instructions

Ganciclovir-d5 (BW 759-d5) is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).

For research use only. We do not sell to patients.

Ganciclovir-d5 Chemical Structure

Ganciclovir-d5 Chemical Structure

CAS No. : 1189966-73-1

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Description

Ganciclovir-d5 (BW 759-d5) is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

260.26

Formula

C9H8D5N5O4

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Ganciclovir-d5
Cat. No.:
HY-13637S
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