2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. SDMA-d6

SDMA-d6  (Synonyms: Symmetric dimethylarginine-d6; NG,NG'-Dimethyl-L-arginine-d6)

Cat. No.: HY-101410S Purity: 99.03%
COA Handling Instructions

Molarity Calculator

SDMA-d6 is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity[1][2].

For research use only. We do not sell to patients.

SDMA-d<sub>6</sub> Chemical Structure

SDMA-d6 Chemical Structure

CAS No. : 1331888-08-4

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1 mg USD 250 In-stock
5 mg USD 900 In-stock
10 mg USD 1250 In-stock
25 mg USD 2050 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of SDMA-d6:

SDMA-d6 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

SDMA-d6 is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SDMA-d6 Related Antibodies
Molecular Weight

208.29

Formula

C8H12D6N4O2
CAS No.
Appearance

Solid-Liquid Mixture

Color

Colorless to off-white

SMILES

OC([C@@H](N)CCC/N=C(NC([2H])([2H])[2H])/NC([2H])([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (600.12 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8010 mL 24.0050 mL 48.0100 mL
5 mM 0.9602 mL 4.8010 mL 9.6020 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.03%

COA (247 KB) HNMR (257 KB) LCMS (107 KB) Elemental Analysis Report (105 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.8010 mL 24.0050 mL 48.0100 mL 120.0250 mL
5 mM 0.9602 mL 4.8010 mL 9.6020 mL 24.0050 mL
10 mM 0.4801 mL 2.4005 mL 4.8010 mL 12.0025 mL
15 mM 0.3201 mL 1.6003 mL 3.2007 mL 8.0017 mL
20 mM 0.2400 mL 1.2002 mL 2.4005 mL 6.0012 mL
25 mM 0.1920 mL 0.9602 mL 1.9204 mL 4.8010 mL
30 mM 0.1600 mL 0.8002 mL 1.6003 mL 4.0008 mL
40 mM 0.1200 mL 0.6001 mL 1.2002 mL 3.0006 mL
50 mM 0.0960 mL 0.4801 mL 0.9602 mL 2.4005 mL
60 mM 0.0800 mL 0.4001 mL 0.8002 mL 2.0004 mL
80 mM 0.0600 mL 0.3001 mL 0.6001 mL 1.5003 mL
100 mM 0.0480 mL 0.2400 mL 0.4801 mL 1.2002 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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SDMA-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDMA-d61331888-08-4Symmetric dimethylarginine-d6NG,NG'-Dimethyl-L-arginine-d6Endogenous MetaboliteInhibitorinhibitorinhibit

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