1 Result for "

simeprevir-13cd3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "simeprevir-13cd3" in MCE Product Catalog:

Art. -Nr.: HY-10241S
Synonyms: TMC435-13C,d3; TMC435350-13C,d3
Simeprevir- 13C,d3 is the 13C- and deuterium labeled Simeprevir. Simeprevir is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses .
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